Emerging Therapeutics for Radioiodide-Refractory Thyroid Cancer

NICOLA, JP; MASINI-REPISO, AM

Journal of Analytical Oncology

Lifescience Global

Lugar: Mississauga; Año: 2016 vol. 5 p. 75 - 75

p class="04-abstract" style="margin: 0in 0in 12pt;">Abstract: Although uncommon, thyroid cancer constitutes the main endocrine neoplasia with an incidence rate that has been increasing steadily over the past decades. Recently, remarkable advances have occurred in understanding the biology of thyroid cancer. Novel germline and somatic point mutations as well as somatic chromosomal rearrangements associated with thyroid carcinogenesis have been discovered. Strikingly, acquired knowledge in the genetics of thyroid cancer has been translated into clinical practice, offering better diagnostic and prognostic accuracy and enabling the development of novel compounds for the treatment of advanced thyroid carcino