Preformulation studies of 5´-O-carbonates of lamivudine with anti HIV and anti HBV activity: Solubility and stability assays

Año: 2014

Development and validation of a stability indicating method for seven novel derivatives of lamivudine with activity anti-HIV and anti-HBV in simulated gastric and intestinal fluids

Lugar: Amsterdam; Año: 2013 vol. 78 p. 52 - 56

Synthesis, physicochemical properties and biological activity against Trypanosoma cruzi of allopurinol derivatives.

Año: 2013 vol. 69C p. 455 - 464

Intestinal Permeability of Lamivudine (3TC) and two Novel 3TC Prodrugs. Experimental and Theoretical Analyses.

Lugar: Amsterdam; Año: 2012

Synthesis, biological evaluation and molecular modeling of 4,6-diarylpyrimidines and diarylbenzenes as novel non-nucleosides HIH-1 reverse transcriptase inhibitors.

Año: 2012 vol. 58 p. 485 - 492

MÓNICA A. RAVIOLO, JOSEP ESTEVE-ROMERO, MARGARITA C. BRIÑÓN

Stability-indicating micellar liquid chromatography method for three novel derivatives of zidovudine in aqueous and simulated gastric and intestinal fluids matrixes

Año: 2011

RAVIOLO MA; BRIÑÓN MC

Preformulation Studies of Zidovudine Derivatives. Dissociation Constants, Differential Scanning Calorimetry Thermogravimetry, X-Ray Powder Diffractometry and Aqueous Stability Studies

Scientia Pharmaceutica; Año: 2011 vol. 79 p. 479 - 491

QUEVEDO, MA; NIETO, LE; BRIÑÓN, MC

P-glycoprotein limits the absorption of the anti-hiv drug zidovudine through rat intestinal segments

Año: 2011 vol. 43 p. 151 - 159

RIBONE, SR.; QUEVEDO, MA; MADRID M; BRIÑÓN, MC

Rational Approaches for the Design of Effective Human Immunodeficiency Virus Type 1 Nonnucleoside Reverse Transcriptase Inhibitors.

Año: 2011 vol. 51 p. 130 - 138

M.A. RAVIOLO, P.A.M. WILLIAMS, S.B. ETCHEVERRY, O.E. PIRO, E.E. CASTELLANO, M.C. BRIÑÓN

Synthesis, molecular structure and physicochemical properties of bis(3´-azido-3´-deoxythymidin-5’-yl) carbonate

Año: 2010 vol. 970 p. 59 - 65

GAGEY, D; RAVETTI, S; CASTRO, EF; GUALDESI, MS; BRIÑÓN MC, CAMPOS, RH; CAVALLARO, LV.

Antiviral activity of 5’-O-Carbonate 2’,3’-dideoxy-3’-thiacytidine prodrugs against Hepatitis B virus in HepG2 2.2.215 cells

Año: 2010 vol. 36 p. 566 - 569

GAGEY, D; RAVETTI, S ; CASTRO, EF; GUALDESI, MS; BRIÑÓN MC; CAMPOS, RH; CAVALLARO, LV

Antiviral activity of 5'-O-Carbonate 2'3'-dideoxy-3'-thiacytidine prodrugs against Hepatitis B virus in HepG2 2.2.215 cells.

Año: 2010 vol. 36 p. 566 - 569

M. A. RAVIOLO, J.S. TRINCHERO-HERNÁNDEZ, G. TURK, M.C. BRIÑÓN

Synthesis and antiretroviral evaluation of novel derivatives of Zidovudina.

Año: 2009 vol. 20 p. 1870 - 1877

- SOLEDAD RAVETTI, MARÍA S GUALDESI, JUAN S TRINCHERO-HERNÁNDEZ, GABRIELA TURK, MC BRIÑÓN

Synthesis and anti-HIV activity of novel 2´,3´-dideoxy-3´-thiacytidine prodrugs.

Año: 2009 vol. 17 p. 6407 - 6413

M.A. QUEVEDO, M.C. BRIÑÓN

In vitro and in vivo pharmacokinetic characterization of two novel prodrugs of zidovudine (AZT).

Año: 2009 vol. 23 p. 103 - 111

S.RAVETTI; M. S GUALDESI; J. S TRINCHERO-HERNÁNDEZ; G. TURK; M.C .BRIÑÓN

Synthesis and anti-HIV activity of novel 2´,3´-dideoxy-3´-thiacytidine prodrugs

Año: 2009 vol. 17 p. 6407 - 6413

M.A. QUEVEDO, S. RIBONE, G.N. MORONI, M.C. BRIÑÓN

. Binding to human serum albumin of AZT and novel AZT derivatives. Experimental and theoretical analysis.

Año: 2008 vol. 16 p. 2779 - 2790

S. RAVETTI ; S. GUALDESI; M.C. BRIÑÓN

Lipophilicity of Novel 5´-Carbonates of Lamivudine with Antiretroviral Activity. Correlation Between Different Methods

Año: 2008 vol. 31 p. 1014 - 1032

M.A. RAVIOLO; J.M. SANCHEZ; M.C. BRIÑÓN; M. A. PERILLO

Determination of Liposome Permeability of Ionizable Carbamates of Zidovudine by Steady State Fluorescente Spectroscopy

Año: 2008 vol. 61 p. 188 - 198

S.A. TEIJEIRO; M.C. BRIÑÓN

3'-Azido-3'-deoxy-5'-O-isonicotinoylthymidine: A Novel Antiretroviral Analog of Zidovudine. III. Solubility Studies

Año: 2006 vol. 25 p. 191 - 202

M.A. QUEVEDO; S.A.TEIJEIRO; M.C. BRIÑÓN

Quantitative Plasma Determination of a Novel Antiretroviral Derivative of Zidovudine, by Solid Phase-Extraction and High Performance Liquid Chromatography

Año: 2006 vol. 385 p. 377 - 384